The CCTST is building on the strengths of the highly successful CCHMC Translational Research Initiative (TRI), utilizing Clinical and Translational Science Award (CTSA) support to expand this intramural funding program for pilot and collaborative research to the entire Academic Health Center (AHC) through the "T1" award program. The Pilot and Collaborative Translational and Clinical Studies (PCS) Core is directed by Bruce Trapnell, MD, MS, professor of pediatrics and assistant director, CCHMC Adult Cystic Fibrosis Center and co-directed by Frank McCormack, MD, professor and director, division of pulmonary, critical care and sleep medicine, UC College of Medicine.

Funding priorities include:

• Investigators new to clinical and translational research
• Collaborations between basic scientists and clinicians
• Interdisciplinary studies, esp. those involving 2 or more AHC institutions (UC east and west campuses, CCHMC, VA Medical Center, University Hospital)

Additional information is available here:

• Table of T1 awards (including T1 Jr. and cores), Year 5, FY 2014
• New T1 Program funding cycle announcement (Year 5, LOI due October 3, 2012)
• Latest T1, T1 Junior and innovative cores program application instructions (Year 5)
• PCS Core Frequently Asked Questions (FAQs)
• Announcement of T1 awards (including T1 Jr. and cores), Year 4, FY 2013
• Table of T1 awards (including T1 Jr. and cores), Year 4, FY 2013
• Table of T1 Junior Investigator Pilot Grant awards, Year 3, FY 2012
• Table of T1 awards, Year 3, FY 2012
• Table of T1 awards, Years 1 & 2, FY 2010-2011 (2 pages)
• News story on Year 2 T1 awards

Just-in-Time Core Funds Grant Program (currently exhausted; new funds available July 1, 2013):

This small grants program is designed to support clinical and translational science investigators who are seeking preliminary data in the next 3-6 months for K23, R01 or similar new or revised extramural grant submissions and need the services of one or more of the institutional cores listed below. Investigators may apply for up to $7,500 annually in support. UC faculty with 80% or greater FTE, including those based at Cincinnati Children’s Hospital Medical Center and Cincinnati Veterans Affairs Medical Center, are generally eligible to apply. Funds are limited and awards are made on a continuing basis, so application early in the fiscal year is encouraged. See the RFA for complete details.

• Just-in-Time Core Funds Grant Program RFA

Just-in-Time Program participating core facilities:

1. Center for Imaging Research (UC)
2. Drug Discovery Center (UC)
3. Genomics & Microarray Laboratory (UC)
4. Proteomics Core Facility (UC)
5. Affymetrix Core (Gene Expression Microarray Core, CCHMC)
6. Human Genetics Core (CCHMC)
7. Cytokine Core (CCHMC)
8. Pathology Core (CCHMC)
9. Imaging Research Center (CCHMC)
10. Echocardiography Core (CCHMC)
11. Research Flow Cytometry Core (CCHMC)
12. Small Animal Heart Core (UC)
13. Clinical Mass Spectrometry (CCHMC)
14. Pharmacometrics Core (UC/CCHMC)
15. Cell Processing and Manipulations Laboratory (CCHMC)
16. Vector Production Facility (CCHMC)
17. Viral Vector Core (CCHMC)
18. Translational Trials Development and Support Laboratory (CCHMC)
19. Diagnostic Immunology Lab (CCHMC)
20. Genetic Variation and Gene Discovery Core Facility-Computational Medicine Center (CCHMC)
21. Center for Autoimmune Genomics and Etiology (CAGE, CCHMC)
22. Protein Informatics Core (UC/CCHMC)
23. Live Microscopy Core (UC)
24. Genetically Modified Mouse Models Core (UC)
25. Pluripotent Stem Cell Facility (CCHMC)
26. Laboratory Animal Medical Services (LAMS, UC)
27. Vontz Core Imaging Laboratory (UC)

 bb.  Confocal Imaging Core (CCHMC)

 cc.  Structural Biology and Protein Expression/Purification Facility (UC)

dd.  Pyrosequencing Lab for Genomic and Epigenomic Research (CCHMC)
 

Retreats/Workshops/Symposia Matching Funds Program 

(new funds available July 1, 2012):

Support is available for multidisciplinary retreats/workshops/symposia (on- or off-campus) that will further the mission of the CCTST. Ideally, these events will provide a rich forum for basic, translational, and clinical scientists to interact and develop new initiatives. Up to $3,000 per event is available from the CCTST, contingent upon the availability of matching funds derived from other sources (typically clinical or research division resources or grants). UC faculty with 80% or greater FTE, including those based at Cincinnati Children’s Hospital Medical Center and Cincinnati Veterans Affairs Medical Center, are generally eligible to apply. Funds are limited and awards are made on a continuing basis, so application early in the fiscal year is encouraged. See link below for complete details.

• Retreats/Workshops/Symposia Matching Funds Program RFA

College of Medicine Discovery Acceleration Initiative

Components include the Provost's Pilot Research Program, Dean's Bridge Funding Program, College of Medicine Study Section, and expanded Just-in-Time Core Funds Grant Program.  The CCTST provides technical support and administration for the PPRP and JIT programs.

• More information
• Provost's Pilot Research Program awardees, fall 2012

For more information on programs of the PCS Core, email catherine.scharf@cchmc.org or call (513) 803-2778.