Clinical and Translational researchers require access to a variety of resources in order to successfully design, plan and execute research projects. The vision of the University of Cincinnati (UC) Academic Health Center (AHC) is to create an environment that facilitates translation of discoveries to application through training and coordination of interdisciplinary teams. To realize this vision, a single point of contact within the Center for Clinical and Translational Science and Training (CCTST), entitled Research Central, has been created to provide support for interdisciplinary clinical and translational research.
Research Central includes personnel who will serve a “concierge” function to provide trainees, entry-level faculty, and more established faculty with little experience in clinical/translational research with resources in protocol development, biostatistical/bioinformatics support, regulatory compliance, and support for investigational new drug (IND) and investigational device exemption (IDE) development and community-based research.
Those accessing Research Central will start by registering their proposed study using our research intake form. This form will ask investigators to record such basic information as study title, proposed need for CCTST resources, etc.
Upon submission, a research proposal will be forwarded to the research methodologist on duty at the BERD core for review. These BERD methodologists are carefully selected personnel with general expertise in research design and methodology, biostatistics, and regulatory issues, as well as in depth knowledge of CCTST resources, priorities, opportunities, and processes.
Upon review of a given proposal, the BERD methodologist will determine the need for further study development, assess the need for additional CCTST resources, prioritize the proposal according to CCTST policies, and add initial comments using an online proposal tracking process. As appropriate, the proposal will then be forwarded to other CCTST consultative services such as Biomedical Informatics and Regulatory Knowledge and Support for their review. In addition, should the BERD methodologist determine that the project would either benefit from or provide potential benefit to any other CCTST groups (e.g. Community Outreach if the proposal might benefit from recruitment of research participants from community practice sites), the proposal may be routed to those groups’ leaders for review and comment back to the investigator.
Our goal is to provide rapid turnaround on an initial proposal response including any suggestions about the need for further proposal revision before proceeding, for additional involvement of CCTST expertise in doing so, and/or for CCTST resource allocation. Should additional assistance from CCTST consultants be needed to refine a proposal, such services will be provided according to CCTST policies. In addition, those projects identified as involving T1 translation or T2 translation will be discussed in a weekly CCTST T1 and T2 (TnT) Meeting. During those meetings, we will discuss the allocation and coordination of CCTST resources to facilitate the projects and overcome the translational block(s). As a result of this comprehensive new service, we anticipate substantial improvements in investigator efficiency and productivity. Complete guidelines are available here.
Become a Member