Pilot Translational and Clinical Studies
Key Upcoming Dates:
-RFA for the next grant cycle will be available September 2019
The Pilot Translational and Clinical Studies (PTC) Core is co-directed by James Geller, MD, professor of pediatrics and medical director, Kidney and Liver Tumors Program, CCHMC, and Dennis McGraw, MD, associate professor, division of pulmonary, critical care and sleep medicine, UC College of Medicine, and director, pulmonary medicine, Cincinnati VA Medical Center.
The Pilot Translational Research and Innovative Core Grant Program supports projects by established principal investigators or by new/early stage investigators mentored by established investigators, and also promotes the establishment of new, innovative cores with a clear translational focus, to build a local or networked infrastructure. Please see details below.
Pilot Translational Research and Innovative Core Grant Program
An integral part of the CCTST mission is stimulating development of pre-clinical and human clinical trials that seek to improve medical care. The CCTST Pilot Translational Research and Innovative Core Grant Program will support projects by established principal investigators, or by new/early stage investigators mentored by established investigators, focused on applying discoveries generated during research in the laboratory, and in preclinical studies, to the development of trials and studies in humans. The Program also promotes the establishment of new, innovative cores with a clear translational focus, to build a local or networked infrastructure.
Translational Research Grant (TRG): Supports established investigators seeking to conduct a novel translational research project. The funding period is limited to one year. The maximum allowable budget (direct costs) is $60,000. Applicants with more than $500,000 in direct costs for research will not be eligible to apply for this grant type.
Mentored Translational Research Grant (MTRG): Supports new and early stage investigators seeking to conduct a novel translational research project. Important requirements of this grant mechanism are the inclusion of a clear letter of support from an established mentor and a detailed description of the Mentee’s training plan and interactions with the mentor. The funding period is limited to one year. The maximum allowable budget (direct costs) is $60,000. Applicants with more than $500,000 in direct costs for research will not be eligible to apply for this grant type.
Innovative Core Grant (ICG): Helps build adequate local infrastructure to support clinical and translational research by providing funds to establish new shared Core facilities with a clear translational focus. The maximum allowable budget (direct costs) is $50,000 per year. The funding period is limited to up to two years.
Applicants seeking a second year of funding for any grant type are required to submit a Letter of Intent and a one page “Progress to Date” report justifying the need for continued support.
Priority will be given to projects which:
- are farthest along in preclinical or early clinical development
- seek to increase communication and collaboration between clinicians or clinical researchers and basic scientists
- seek to increase collaboration between investigators in different institutions within the Academic Health Center (AHC). The program is particularly interested in promoting collaborations between investigators at UCMC and CCHMC and between investigators at either UCMC or CCHMC and those at UC’s west campus.
- have clearly described plans to utilize the results as preliminary data in an application soliciting extramural funding
- are focused on new research or technological development with a high likelihood of leading to patent or licensing opportunities
When and as appropriate, consideration will be given to proposals that promote interactions between AHC investigators and members of the community.
Investigators with a faculty appointment of at least 80% FTE at the AHC (UC, UCMC, CCHMC, VAMC) or UC west campus, including basic scientists, physicians, nurses, and other health care faculty with advanced degrees (MD, PhD, MD-PhD, or equivalent) are potentially eligible. The PI or Co-I who is applying must either currently hold a faculty appointment at UC or CCHMC or expect to hold one at the time of the award at the level of Instructor, Assistant Professor, Research Assistant Professor, Associate Professor, or Professor. Collaborative teams of investigators spanning disciplines and programs made up of basic and clinical faculty are strongly encouraged to apply. See the program announcement for complete details on eligibility. Applicants must be CCTST members. Join here free of charge.
LOIs and invited full applications must be submitted through the CCTST Competition and Awards Program Site (CCAPS). Log in using your UC (“6+2”) or CCHMC username and password.
- Table of Awards, FY 2020 (Year 4)
- Table of awards, FY 2019 (Year 3)
- Table of awards, FY 2018 (Year 2)
- Table of awards, FY 2017 (Year 1)
Information on the former T1 program
- Table of most recent T1 awards (including T1 Jr. and cores), Year 7, FY 2016
- T1 request for applications, Year 7, FY 2016
- Table of T1 awards (including T1 Jr. and cores), Year 6, FY 2015
- Table of T1 awards (including T1 Jr. and cores), Year 5, FY 2014
- Announcement of T1 awards (including T1 Jr. and cores), Year 4, FY 2013
- Table of T1 awards (including T1 Jr. and cores), Year 4, FY 2013
- Table of T1 Junior Investigator Pilot Grant awards, Year 3, FY 2012
- Table of T1 awards, Year 3, FY 2012
- Table of T1 awards, Years 1 & 2, FY 2010-2011 (2 pages)
- News story on Year 2 T1 awards
More Grant Programs
Just-In-Time Core Grant Program
The mission of the Just-In-Time (JIT) grant mechanism is to enable investigators to use UC or CCHMC Core facilities to obtain critical data for submission of a competitive extramural proposal, patent application or commercialization agreement.
more details about Just-In-Time Core Grant Program…
Processes and Methods Pilot Grant Program
This pilot grant mechanism enables investigators at all levels to explore ways to improve the efficiency and effectiveness of the processes and methods used in clinical and translational research.
more details about Processes and Methods Pilot Grant Program…
Retreats/Workshops/Symposia Matching Funds Program
Support is available for multidisciplinary retreats/workshops/symposia (on- or off-campus) that will further the mission of the CCTST.
more details about Retreats/Workshops/Symposia Matching Funds Program…
For more information on programs of the PTC Core, email Jim Geller.