Clinical Translational Research Center (CTRC)
The Clinical Translational Research Center (CTRC), formerly the General Clinical Research Center (GCRC), provides the resources to perform high quality, patient-oriented research across the Academic Health Center (AHC) and the community. Funded by a NIH Clinical and Translational Science Award (CTSA) and based at CCHMC, the CTRC is led by Mark Mitsnefes, MD, MS.
The CTRC operates and provides all clinical implementation services in the new Schubert Research Clinic, which is located on the first floor of the Clinical Sciences Pavilion (Location T) which opened in 2016 on the CCHMC main campus. The clinic is a welcoming and bright space conveniently located between the main hospital and the research buildings. This space brings together all services supporting clinical trials in one location, making the process of planning and conducting trials convenient for both investigator and participant.
The Schubert Research Clinic includes 28 exam rooms, one preparatory lab with equipment for processing samples, a packaging and shipping room, a metabolic kitchen, a body composition laboratory with DXA scanners, and a vascular research laboratory. The Clinic can accommodate visits of less than ½ hour to greater than 10 hours and is equipped for subjects from infants to seniors. The clinic is fully staffed with highly trained and skilled nurses, medical assistants, research assistants, and registration staff to help with study visit needs. Access to the Schubert Research Clinic is open to any clinical researcher with a currently approved IRB study.
The clinic provides experienced research nurses to assist with protocol implementation. The research protocol nurses help the investigator coordinate all activities across different departments needed to implement the protocol, including investigational pharmacy, CCHMC lab, radiology, etc. Detailed study-specific physician orders and data collection flow sheets are developed for the protocol. The clinic research nurses provide a unique, concierge-like service to aid investigators in accessing the appropriate services available.
The clinic research nurses maintain contact with the investigator throughout the duration of the study to ensure positive outcomes and continue to monitor the research study until its completion. The research nurses are trained in guided IV placement utilizing a portable ultrasound that is available to all research studies. The nurses are available to assist with studies involving blood draws, sample processing and other study-related activities including full-day pharmacokinetic studies.
The Sample Processing Lab is located adjacent to the outpatient facility. This laboratory includes a refrigerated centrifuge for specimen processing, a -20°C freezer and ultralow freezers for specimen storage, and a YSI glucose analyzer for protocols that need immediate glucose results. Samples of blood, urine, stool, bile, etc. are processed and stored according to protocol.
Off-Unit Clinical Research Nursing
Off-unit clinical research nursing is available to support studies performed outside the unit at CCHMC (i.e. the Regional Center for Newborn Intensive Care, Pediatric Intensive Care Unit, and psychiatric unit) and subjects in beds in CCHMC inpatient units (scatterbeds). The research nurse team is accredited to participate in studies performed across the AHC and community, including UC Medical Center. A 3,000 sq.ft. satellite VA Clinical Research Unit (CRU) is available at Cincinnati Veterans Affairs Medical Center for studies in adults.
- Biochemistry Core Laboratory (specialized research tests for studies)
- Bionutrition and Body Composition Core (research nutrition assessments, DXA, pQCT)
- Behavioral Core (intellectual/developmental testing, specialized neuropsychological testing)
- Vascular Core (vascular measures, including peripheral arterial stiffness testing, and vascular data management)
For Assistance or More Information
- Learn about the new Schubert Research Clinic in the CCHMC Clinical Sciences Pavilion (Location T)
- Questions? Contact email@example.com
- Contact director of clinical operations Rebecca Harper, DNP, RN, CPN
- Contact CTRC business manager Amy Hartkemeyer
- Contact VA CRU administrator/nurse manager Colleen Rogge, RN, BSN, CCRC
- Accurint study participant locating service
- Clinical Research Feasibility Fund (CReFF) pilot grant program for junior faculty
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